Cell综述-健身锻炼背后的生物学

运动其实很复杂，包含很多知识，先睹为快！

Exercise represents a major challenge to whole-body homeostasis provoking widespread perturbations

in numerous cells, tissues, and organs that are caused by or are a response to the increased

metabolic activity of contracting skeletal muscles. To meet this challenge, multiple integrated and

often redundant responses operate to blunt the homeostatic threats generated by exerciseinduced

increases in muscle energy and oxygen demand. The application of molecular techniques

to exercise biology has provided greater understanding of the multiplicity and complexity of cellular

networks involved in exercise responses, and recent discoveries offer perspectives on the mechanisms

by which muscle ‘‘communicates’’ with other organs and mediates the beneficial effects

of exercise on health and performance.​​​